Cambridge University Hospitals NHS Foundation Trust (CUH) is one of the largest and best known trusts in the country, delivering high-quality patient care through Addenbrooke’s and the Rosie Hospitals. CUH is a leading national centre for specialist treatment for rare or complex conditions and a university teaching hospital with a worldwide reputation.
CUH is a key partner in Cambridge University Health Partners (CUHP), one of only six academic health science centres in the UK, and is at the heart of the development of the Cambridge Biomedical Campus (CBC), which brings together on one site world-class biomedical research, patient care and education. As part of the Campus development, Papworth Hospital has created a bespoke, purpose-built hospital, and AstraZeneca has established a new global R&D centre and corporate headquarters. The Campus is one of the Government’s National Institute for Health Research (NIHR) comprehensive biomedical research centres.
The EpiCov database of de‐identified routinely collected data from Cambridge University Hospitals includes data from the electronic hospital notes system (Epic), pathology test measurement results (including high dimensional data generated by routine tests which are typically destroyed), the imaging system (PACS), and other COVID‐19 relevant hospital information systems. The database currently contains data from approximately 350,000 pseudonymised patient records, including patients diagnosed with COVID‐19 or suspected of having COVID‐19, and patients and consented population cohorts who provide a control for variation in age, season, and gender within a large enough dataset to apply machine learning to identify clinical signatures or variations unique to COVID‐19. A Data Access Committee considers all applications, and access to variables is only authorised if they are deemed important to the proposed analysis.
The ‘Inpatient health records of older adults’ database includes electronic health records of all patients 65 years or older admitted non‐electively to Addenbrooke’s Hospital since EPIC hospital records began in October 2014 is held at the European Molecular Biology Laboratory ‐ European Bioinformatics Institute (EMBL‐EBI). Longitudinal descriptors including investigations, physiological measurements, drug treatments and outcome variable provide a heterogenous, high‐dimensional dataset to develop machine learning algorithms. Details, including a statement on data availability, can be found here
The NIHR BioResource is a recallable resource of over 200,000 volunteers from the general population, and patients with rare and common diseases who have provided biosamples for analysis, including DNA, and consent for access to health records. Data that can be accessed include genetic and linked phenotypic data. To apply for BioResource data access, click here.
The Gut Reaction HDR UK Data Research Hub is collating data from multiple sources on patients recruited to the NIHR Inflammatory Bowel Diseases BioResource. Data from electronic health records at 9 NHS Trusts is being combined with research data, including genomic data.
Roland Sinker, Chief Executive of Cambridge University Hospitals said: ‘Cambridge University Hospitals is committed to the safe and secure use of data to improve health, and delighted to be part of the Health Data Research UK Alliance.’